An autolysin ring associated with cell separation of Staphylococcus aureus
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چکیده
منابع مشابه
An autolysin ring associated with cell separation of Staphylococcus aureus.
atl is a newly discovered autolysin gene in Staphylococcus aureus. The gene product, ATL, is a unique, bifunctional protein that has an amidase domain and a glucosaminidase domain. It undergoes proteolytic processing to generate two extracellular peptidoglycan hydrolases, a 59-kDa endo-beta-N-acetylglucosaminidase and a 62-kDa N-acetylmuramyl-L-alanine amidase. It has been suggested that these ...
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Despite intense efforts by the medical and pharmaceutical communities, Staphylococcus aureus continues to be a pervasive pathogen that causes a myriad of diseases and a high level of morbidity and mortality among infected patients. Thus, discovering or designing novel therapeutics able to kill both drug-resistant and drug-sensitive S. aureus remains a top priority. Bacteriolytic enzymes, mostly...
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Background: Staphylococcal aureus is a gram positive cocci and opportunistic pathogen. Due to the spread of this bacterium to antibiotics resistance, one of the most important ways of prevention is the use of vaccines. In this respect, autolysin protein as one of the adhesion molecule of bacteria plays an important role for binding bacteria to the host cells and cell division. Herein, the role ...
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In the present study, the therapeutic potential of bacteriophages virulent to Staphylococcus aureus associated with goat mastitis were isolated, identified and assessed. Staphylococcus aureus (host or indicator bacterium) was isolated from a goat suffering from clinical mastitis. Based on cultural, morphological, biochemical tests and amplification of S. aureus specific thermonuclease gene inPC...
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Renal lesions commonly seen in SBE include localized infarcts, abscesses, therapy-related interstitial nephritis, and glomerulonephritis ( 1-2). The incidence of glomerulonephritis associated with SBEhas not been determined. The most commonorganisms leading to SBEare the streptococcus viridans group and coagulase-negative staphylococci, including Staphylococcus (Staph.) epidermidis ( 1). The re...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1996
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.178.6.1565-1571.1996